The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2009
Filed:
Nov. 24, 2004
Arielle Genevois-borella, Thiais, FR;
Jean-luc Malleron, Marcoussis, FR;
Jean Bouquerel, Drancy, FR;
Gilles Doerflinger, Les Ulis, FR;
Andrees Bohme, Paris, FR;
Gaetan Touyer, Chelles, FR;
Jean-francois Sabuco, Paris, FR;
Corrine Terrier, Livry Gargan, FR;
Serge Mignani, Chatenay-Malabry, FR;
Michel Evers, La Queue en Brie, FR;
Youssef El-ahmad, Creteil, FR;
Arielle Genevois-Borella, Thiais, FR;
Jean-Luc Malleron, Marcoussis, FR;
Jean Bouquerel, Drancy, FR;
Gilles Doerflinger, Les Ulis, FR;
Andrees Bohme, Paris, FR;
Gaetan Touyer, Chelles, FR;
Jean-Francois Sabuco, Paris, FR;
Corrine Terrier, Livry Gargan, FR;
Serge Mignani, Chatenay-Malabry, FR;
Michel Evers, La Queue en Brie, FR;
Youssef El-Ahmad, Creteil, FR;
Aventis Pharma S.A., Antony, FR;
Abstract
The present invention relates to the novel derivatives of formula (I) in which A is, if it is present, a (C1-C6) alkyl, a (C3-C6) alkenyl, a (C3-C6) alkynyl, a (C3-C7) cycloalkyl or a (C5-C7) cycloalkenyl, R1 is an NR6R7, (C4-C7) azacycloalkyl, (C5-C7) azacycloalkenyl, (C5-C9) azabicycloalkyl or (C5-C9) azabicycloalkenyl group; A-R1 is such that the nitrogen of R1 and the nitrogen in the 1-position of the pyrazole are necessarily separated by at least two carbon atoms, R3 is an H, halogen, OH, SH, NH, ORc, SRc, SORa, SORa, NHCHO, NRaRb, NHC(O)Ra, NHC(S)Ra or NHSORa, R4 is an aryl or heteroaryl; and R5 is an H, halogen, CF, CHF, CHF, linear or branched (C1-C6) alkyl or (C3-C7) cycloalkyl, to their racemates, enantiomers and diastereoisomers and to their mixtures, their tautomers and to their pharmaceutically acceptable salts.