The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2009
Filed:
Apr. 12, 2001
Applicants:
Richard C. Austin, Ancaster, CA;
Anthony K. C. Chan, Ancaster, CA;
Leslie Roy Berry, Burlington, CA;
Inventors:
Richard C. Austin, Ancaster, CA;
Anthony K. C. Chan, Ancaster, CA;
Leslie Roy Berry, Burlington, CA;
Assignee:
McMaster University and Hamilton Health Sciences Corporation, Hamilton, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides methods for preventing the generation of active thrombin on the surface of cells. The present methods are based upon the surprising discovery that expression or activation of an ER resident chaperone protein in a cell inhibits the generation of thrombin on the surface of the cell. Accordingly, expressing or activating an ER resident chaperone protein can be used to treat or prevent any of a number of thrombotic diseases.