The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 28, 2009
Filed:
Sep. 06, 2000
Applicants:
Richard William Titball, Salisbury, GB;
Helen Lisa Bullifent, Salisbury, GB;
Inventors:
Richard William Titball, Salisbury, GB;
Helen Lisa Bullifent, Salisbury, GB;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A01N 63/00 (2006.01); C12N 15/00 (2006.01); C12N 15/09 (2006.01); C12P 21/06 (2006.01); C12P 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
A method of enhancing expression of a desired protein at mucosal effector sites, the method including placing the protein to be expressed under the control of a promoter having SEQ ID NO: 2, SEQ ID NO: 3 or SEQ ID NO: 4, or a fragment or variant of any of these that has promoter activity, and causing expression in mucosal cells. Constructs used in the methods, as well as suitable recombinant gut-colonising microorganisms such as aspp., are also described. Such organisms are useful in the preparation of vaccines.