The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2009

Filed:

Jun. 26, 2002
Applicants:

Rajiv Khanna, Herston, AU;

Rebecca Ann Elkington, Manly, AU;

Susan Jennifer Walker, Taringa, AU;

Inventors:

Rajiv Khanna, Herston, AU;

Rebecca Ann Elkington, Manly, AU;

Susan Jennifer Walker, Taringa, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/245 (2006.01); C07K 7/06 (2006.01); C12Q 1/70 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides CTL epitope peptides and polyepitope peptides from 14 distinct antigens of human cytomegalovirus (HCMV) that are restricted through HLA the most commonly prevalent class I alleles in different ethnic populations of the world. These epitopes provide an important platform for CTL epitope-based vaccines against HCMV. The present invention further provides vaccine compositions comprising the subject epitope and polyepitope peptides and methods for vaccination of humans and for the adoptive transfer of HCMV-specific T cells to human subjects. The present invention further provides reagents and methods for determining the HCMV status or level of HCMV-specific immunity of a subject.


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