The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2009
Filed:
Dec. 08, 2004
Yanzhong Wu, Bronx, NY (US);
Arkadiy Rubezhov, West Nyack, NY (US);
Jean Schmid, Chester, NY (US);
Jay Thomas Afragola, Spring Valley, NY (US);
Yanzhong Wu, Bronx, NY (US);
Arkadiy Rubezhov, West Nyack, NY (US);
Jean Schmid, Chester, NY (US);
Jay Thomas Afragola, Spring Valley, NY (US);
Wyeth, Madison, NJ (US);
Abstract
There is provided a process for the preparation of substituted amino alcohols HO—(CH)—NRRfrom haloalcohols HO—(CH)—X, where X is Cl, Br or I, by reaction with an amine HNRR, in water as solvent at a temperature range of about 20° C. to about 90° C. optionally in the presence of a catalytic amount of an iodide source metal iodides. The haloalcohols are useful in the preparation of 6-[(substituted)phenyl]-triazolopyrimidine compounds which are useful in the treatment of cancer.