The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 2009

Filed:

Jan. 05, 2006
Applicants:

Wenxue Wu, Princeton Junction, NJ (US);

Loc Thanh Tran, Parsippany, NJ (US);

Bosco D'sa, Edison, NJ (US);

Feng Liang, Monmouth Junction, NJ (US);

William Leong, Westfield, NJ (US);

Hong-chang Lee, Livingston, NJ (US);

Kevin Klopfer, Flemington, NJ (US);

Vijay Sabesen, Millbrae, CA (US);

Inventors:

Wenxue Wu, Princeton Junction, NJ (US);

Loc Thanh Tran, Parsippany, NJ (US);

Bosco D'Sa, Edison, NJ (US);

Feng Liang, Monmouth Junction, NJ (US);

William Leong, Westfield, NJ (US);

Hong-Chang Lee, Livingston, NJ (US);

Kevin Klopfer, Flemington, NJ (US);

Vijay Sabesen, Millbrae, CA (US);

Assignee:

Schering Corporation, Kenilworth, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); C07D 239/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is generally directed to a process to directly prepare pharmaceutically acceptable salts enriched with respect to selected rotameric salts of a basic compound, by creative choice of an acid and a solvent medium. The process is particularly useful in preparing specific rotamers of pharmaceutically useful salts in desired preponderance of a rotamer.


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