The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2009
Filed:
Dec. 03, 2004
Seetharama A. Acharya, Cresskill, NJ (US);
Parimala Nacharaju, Staten Island, NY (US);
Belur N. Manjula, Cresskill, NJ (US);
Seetharama A. Acharya, Cresskill, NJ (US);
Parimala Nacharaju, Staten Island, NY (US);
Belur N. Manjula, Cresskill, NJ (US);
Albert Einstein College of Medicine of Yeshiva University, Bronx, NY (US);
Abstract
The present invention is directed to pegylated red blood cells comprising a polyethylene glycol (PEG) attached to a thiolated amino group on a membrane protein, and to compositions comprising the pegylated red blood cells. The invention also provides methods of preparing pegylated red blood cells comprising reacting red blood cells with a compound that produces a thiolated amino group on a red blood cell membrane protein, and reacting the thiolated red blood cell with a PEG. The invention further provides methods of treatment using pegylated red blood cells.