The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2009
Filed:
Apr. 12, 2006
Aaron Rulison, Los Altos, CA (US);
Jeffrey A. Wolk, Half Moon Bay, CA (US);
Ernest C.w. Lee, Palo Alto, CA (US);
Michael Slater, Modesto, CA (US);
Morten J. Jensen, San Francisco, CA (US);
Aaron Rulison, Los Altos, CA (US);
Jeffrey A. Wolk, Half Moon Bay, CA (US);
Ernest C.W. Lee, Palo Alto, CA (US);
Michael Slater, Modesto, CA (US);
Morten J. Jensen, San Francisco, CA (US);
Caliper LifeSciences, Inc., Mountain View, CA (US);
Abstract
An optical detection system for a microfluidic device and a dry-focus microfluidic device compatible with the compact optical detection system are described. The system includes an LED; means for collimating light emitted by the LED; an aspherical, fused-silica objective lens; means for directing the collimated light through the objective onto a microfluidic device; and means for detecting a fluorescent signal emitted from the microfluidic device. The working distance between the objective and the device allows light from an external LED or laser to be brought in along a diagonal path to illuminate the microfluidic device. The dry-focus microfluidic device includes multiple channels and multiple closed optical alignment marks having curved walls. At least one of the channels is positioned between at least two of the marks. The marks are illuminated for alignment and focusing purposes by light brought in on a diagonal path from an external white LED.