The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2009
Filed:
Oct. 17, 2005
Lawrence J. Wangh, Auburndale, MA (US);
John Rice, Quincy, MA (US);
J. Aquiles Sanchez, Framingham, MA (US);
Kenneth Pierce, Natick, MA (US);
Jesse Salk, Seattle, WA (US);
Arthur Reis, Arlington, MA (US);
Cristina Hartshorn, Needham, MA (US);
Lawrence J. Wangh, Auburndale, MA (US);
John Rice, Quincy, MA (US);
J. Aquiles Sanchez, Framingham, MA (US);
Kenneth Pierce, Natick, MA (US);
Jesse Salk, Seattle, WA (US);
Arthur Reis, Arlington, MA (US);
Cristina Hartshorn, Needham, MA (US);
Brandeis University, Waltham, MA (US);
Abstract
An additive for preventing mispriming in polymerase chain reaction (PCR) amplifications and assays comprising a hairpin oligonucleotide having a stem duplex greater than six nucleotides in length and a stabilized stem terminus. The additive improves PCR amplifications, including LATE-PCR amplifications when added to initial amplification reaction mixtures. It can be included in oligonucleotide sets and in kits for PCR amplification and assays.