The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2009

Filed:

Apr. 16, 2003
Applicants:

Yoshiyuki Matsumoto, Tokyo, JP;

Minoru Imai, Tokyo, JP;

Yoshiyuki Sawai, Tokyo, JP;

Susumu Takeuchi, Tokyo, JP;

Akinobu Nakanishi, Tokyo, JP;

Kunio Minamizono, Tokyo, JP;

Tomonori Yokoyama, Tokyo, JP;

Inventors:

Yoshiyuki Matsumoto, Tokyo, JP;

Minoru Imai, Tokyo, JP;

Yoshiyuki Sawai, Tokyo, JP;

Susumu Takeuchi, Tokyo, JP;

Akinobu Nakanishi, Tokyo, JP;

Kunio Minamizono, Tokyo, JP;

Tomonori Yokoyama, Tokyo, JP;

Assignee:

Teijin Limited, Osaka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); A61K 31/4523 (2006.01); A61K 31/454 (2006.01); A61P 11/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides low molecular compounds having activity which inhibits binding of CCR3 ligands to CCR3 on target cells, i.e. CCR3 antagonists. The invention also provides compounds represented by formula (I) below, pharmaceutically acceptable acid adducts thereof, or pharmaceutically acceptable C-Calkyl adducts thereof, as well as pharmaceutical compositions comprising them as effective ingredients, which are useful for treatment or prevention of diseases associated with CCR3, such as asthma and allergic rhinitis.


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