The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2009

Filed:

Jun. 13, 2006
Applicants:

Jung-shou Chen, Foster City, CA (US);

William A. Garland, San Clemente, CA (US);

Inventors:

Jung-Shou Chen, Foster City, CA (US);

William A. Garland, San Clemente, CA (US);

Assignees:

Biocheck, Inc., Foster City, CA (US);

Angiogenex, Inc., New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); C12N 5/18 (2006.01); G01N 33/53 (2006.01); G01N 33/543 (2006.01); G01N 33/574 (2006.01); C07H 21/04 (2006.01); C12P 21/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a rabbit monoclonal antibody that binds to human Id1 protein and/or mouse Id1 protein with high specificity and high affinity. The antibody has a binding constant, measured with respect to human Id1 protein and/or mouse Id1 protein, equal to or greater than 1×10/molar. The antibody has no substantial cross-reactivity with other family Id proteins such as Id2, Id3, or Id4, or other endogenous proteins present in the cells that express Id1 protein. The high specificity and high affinity of the rabbit monoclonal antibodies of the present invention allows sensitive and specific detection and/or quantitation of Id1 protein in biological samples. The antibodies are useful in immunochemical-based assays such as ELISA, western blot, and immunohistochemical staining.


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