The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2009
Filed:
Jul. 31, 2003
Rüdiger Ridder, Schriesheim, DE;
Wolfgang Rudy, Bretten, DE;
Matthias Herkert, Heidelberg, DE;
Marcus Trunk-gehmacher, Heidelberg, DE;
Anja Reichert, Nuβloch, DE;
Magnus Von Knebel Doeberitz, Heidelberg Ziegelhausen, DE;
Rüdiger Ridder, Schriesheim, DE;
Wolfgang Rudy, Bretten, DE;
Matthias Herkert, Heidelberg, DE;
Marcus Trunk-Gehmacher, Heidelberg, DE;
Anja Reichert, Nuβloch, DE;
Magnus Von Knebel Doeberitz, Heidelberg Ziegelhausen, DE;
MTM Laboratories, AG, Heidelberg, DE;
Abstract
This invention provides methods for improved diagnosis of medically relevant conditions by solution based biochemical testing procedures performed in solutions of test samples. The invention provides a method to substitute the cell based morphological information contained within the cytological and/or histological data of the test sample by molecular information obtainable from the solution, wherein the original test sample is dissolved and thus enables for accurate and reproducible assessment of medically relevant diagnosis from dissolved test samples. The method according to the invention comprises the steps of determining the levels of one or more disease markers associated with the condition to be diagnosed, determining the level of one or more normalization markers suitable to substitute the information related to morphological aspects of the sample, comparing and/or combining the data of the disease and normalization markers, and assessing diagnosis of a medically relevant condition.