The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2009

Filed:

Jun. 02, 2004
Applicants:

Irina A. Sokolova, Villa Park, IL (US);

Steven A. Seelig, Elmhurst, IL (US);

Larry E. Morrison, Glen Ellyn, IL (US);

Walter King, Wheaton, IL (US);

Alicia Algeciras-schimnich, Naperville, IL (US);

Inventors:

Irina A. Sokolova, Villa Park, IL (US);

Steven A. Seelig, Elmhurst, IL (US);

Larry E. Morrison, Glen Ellyn, IL (US);

Walter King, Wheaton, IL (US);

Alicia Algeciras-Schimnich, Naperville, IL (US);

Assignee:

VYSIS, Inc., Downers Grove, IL (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12P 19/34 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods of using probes and probe sets for the detection of high grade dysplasia and carcinoma in cervical cells are described. Methods of the invention include hybridizing one or more chromosomal probes to a biological sample obtained from a subject and detecting the hybridization pattern of the chromosomal probes to the sample to determine whether the subject has high grade dysplasia or carcinoma. Methods of the invention also include preliminary screening the cells for a marker associated with a risk for cancer, and preferably involves screening for HPV infected cells by in situ hybridization using an HPV probe mixture.


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