The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2009

Filed:

Jun. 17, 2003
Applicants:

Richard Bucala, Cos Cob, CT (US);

Robert A. Mitchell, New York, NY (US);

Jurgen Bernhagen, New York, NY (US);

Thierry F. Calandra, New York, NY (US);

Anthony Cerami, Shelter Island, NY (US);

Inventors:

Richard Bucala, Cos Cob, CT (US);

Robert A. Mitchell, New York, NY (US);

Jurgen Bernhagen, New York, NY (US);

Thierry F. Calandra, New York, NY (US);

Anthony Cerami, Shelter Island, NY (US);

Assignee:

Cytokine PharmaSciences, Inc., King of Prussia, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 16/18 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compositions and methods for inhibiting the release and/or biological activity of migration inhibitory factor (MIF). In particular, the invention relates to the uses of such compositions and methods for the treatment of various conditions involving cytokine-mediated toxicity, which include, but are not limited to shock, inflammation, graft versus host disease, and/or autoimmune diseases.


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