The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2009

Filed:

Jan. 11, 2007
Applicants:

Qingping Zeng, Thousand Oaks, CA (US);

John G. Allen, Newbury Park, CA (US);

Matthew P. Bourbeau, Woodland Hills, CA (US);

Celia Dominguez, Los Angeles, CA (US);

Christopher H. Fotsch, Thousand Oaks, CA (US);

Nianhe Han, Thousand Oaks, CA (US);

Fang-tsao Hong, Thousand Oaks, CA (US);

Xin Huang, Roslindale, MA (US);

Matthew R. Lee, Calabasas, CA (US);

Aiwen LI, Westlake Village, CA (US);

Qingyian Liu, Camarillo, CA (US);

James T. Rider, Camarillo, CA (US);

Seifu Tadesse, Simi Valley, CA (US);

Andrew S. Tasker, Simi Valley, CA (US);

Vellarkad N. Viswanadhan, Thousand Oaks, CA (US);

Xianghong Wang, Moorpark, CA (US);

Kurt E. Weiler, Thousand Oaks, CA (US);

George E. Wohlhieter, Lake Balboa, CA (US);

Guomin Yao, Newbury Park, CA (US);

Chester Chenguang Yuan, Newbury Park, CA (US);

Inventors:

Qingping Zeng, Thousand Oaks, CA (US);

John G. Allen, Newbury Park, CA (US);

Matthew P. Bourbeau, Woodland Hills, CA (US);

Celia Dominguez, Los Angeles, CA (US);

Christopher H. Fotsch, Thousand Oaks, CA (US);

Nianhe Han, Thousand Oaks, CA (US);

Fang-Tsao Hong, Thousand Oaks, CA (US);

Xin Huang, Roslindale, MA (US);

Matthew R. Lee, Calabasas, CA (US);

Aiwen Li, Westlake Village, CA (US);

Qingyian Liu, Camarillo, CA (US);

James T. Rider, Camarillo, CA (US);

Seifu Tadesse, Simi Valley, CA (US);

Andrew S. Tasker, Simi Valley, CA (US);

Vellarkad N. Viswanadhan, Thousand Oaks, CA (US);

Xianghong Wang, Moorpark, CA (US);

Kurt E. Weiler, Thousand Oaks, CA (US);

George E. Wohlhieter, Lake Balboa, CA (US);

Guomin Yao, Newbury Park, CA (US);

Chester Chenguang Yuan, Newbury Park, CA (US);

Assignee:

Amgen, Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/425 (2006.01); C07D 277/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to thiazole compounds of Formula I and Formula II and compositions thereof useful for treating diseases mediated by protein kinase B (PKB) where the variables have the definitions provided herein. The invention also relates to the therapeutic use of such thiazole compounds and compositions thereof in treating disease states associated with abnormal cell growth, cancer, inflammation, and metabolic disorders.


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