The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2009

Filed:

May. 23, 2005
Applicants:

Carl Alan Busacca, Poughkeepsie, NY (US);

Rogelio Perez Frutos, Sandy Hook, CT (US);

Nizar Haddad, Danbury, CT (US);

Suresh R. Kapadia, Danbury, CT (US);

Jon Charles Lorenz, New Milford, CT (US);

Anjan Saha, Hamden, CT (US);

Chris Hugh Senanayake, Brookfield, CT (US);

Xudong Wei, Ridgefield, CT (US);

Inventors:

Carl Alan Busacca, Poughkeepsie, NY (US);

Rogelio Perez Frutos, Sandy Hook, CT (US);

Nizar Haddad, Danbury, CT (US);

Suresh R. Kapadia, Danbury, CT (US);

Jon Charles Lorenz, New Milford, CT (US);

Anjan Saha, Hamden, CT (US);

Chris Hugh Senanayake, Brookfield, CT (US);

Xudong Wei, Ridgefield, CT (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/38 (2006.01); A61K 31/44 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are highly convergent processes for preparing compounds of formula (I), which compounds are potent active agents for the treatment of hepatitis C virus (HCV) infection: The disclosed processes use SAr-type coupling reactions between peptidic compounds having a hydroxyproline moiety of the following formula: and halogenated or sulfonated bromoquinoline compounds.


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