The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2009

Filed:

Sep. 15, 2004
Applicants:

Bing Wang, Cupertino, CA (US);

Gail Walkinshaw, Mountain View, CA (US);

Sekhar Boddupalli, San Jose, CA (US);

Arkadij M. Elizarov, Castro Valley, CA (US);

Xianming Jin, Fremont, CA (US);

Xianfeng LI, Cupertino, CA (US);

Donald R. James, El Sobrante, CA (US);

Jiangao Song, Cupertino, CA (US);

Jian Chen, Sunnyvale, CA (US);

Wei Zhang, Santa Clara, CA (US);

Inventors:

Bing Wang, Cupertino, CA (US);

Gail Walkinshaw, Mountain View, CA (US);

Sekhar Boddupalli, San Jose, CA (US);

Arkadij M. Elizarov, Castro Valley, CA (US);

Xianming Jin, Fremont, CA (US);

Xianfeng Li, Cupertino, CA (US);

Donald R. James, El Sobrante, CA (US);

Jiangao Song, Cupertino, CA (US);

Jian Chen, Sunnyvale, CA (US);

Wei Zhang, Santa Clara, CA (US);

Assignee:

Edison Pharmaceuticals, Inc., San Jose, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/355 (2006.01); A61K 31/427 (2006.01); A61K 31/4152 (2006.01); C07D 311/72 (2006.01); C07D 405/06 (2006.01); C07D 417/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to novel chroman derivatives, stereoisomers and pharmaceutically acceptable salts of Formula I wherein the substituents are as defined in the specification. They are useful in the treatment of disorders mediated by lipoxygenase, such as immune diseases, respiratory diseases and cardiovascular diseases, as well as in the treatment of neurodegenerative disorders and/or mitochondrial disorders. They are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.


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