The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2009
Filed:
Jun. 10, 2002
Satoshi Omura, Tokyo, JP;
Kazuro Shiomi, Tokyo, JP;
Hiroshi Tomoda, Tokyo, JP;
Rokuro Masuma, Tokyo, JP;
Kiyoshi Kita, Tokyo, JP;
Satoshi Omura, Tokyo, JP;
Kazuro Shiomi, Tokyo, JP;
Hiroshi Tomoda, Tokyo, JP;
Rokuro Masuma, Tokyo, JP;
Kiyoshi Kita, Tokyo, JP;
The Kitasato Institute, Tokyo, JP;
Abstract
An electron transport system complex II inhibitor comprising 2-pyridinol derivative represented by the general formula [I] wherein R is alkyl or alkenyl optionally having substituent containing halogen, or its tautomer 2-pyridone derivative represented by the general formula [II] wherein R is alkyl or alkenyl optionally having substituent containing halogen, or salt thereof as an active ingredient. The compound inhibits the complex II strongly with nM order activity. Consequently, 2-pyridinol derivative or its tautomer, 2-pyridone derivative, are useful as the complex II inhibitor.