The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2009
Filed:
Dec. 17, 2003
Applicants:
Frans Eduard Janssens, Bonheide, BE;
François Maria Sommen, Wortel, BE;
Benoît Christian Albert Ghislain DE Boeck, Genval, BE;
Joseph Elisabeth Leenaerts, Rijkevorsel, BE;
Inventors:
Frans Eduard Janssens, Bonheide, BE;
François Maria Sommen, Wortel, BE;
Benoît Christian Albert Ghislain De Boeck, Genval, BE;
Joseph Elisabeth Leenaerts, Rijkevorsel, BE;
Assignee:
Janssen Pharmaceutica N.V., Beerse, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 25/00 (2006.01); A61K 31/55 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention concerns substituted 4-(4-piperidin-4-yl-piperazin-1-yl)-azepane derivatives having neurokinin antagonistic activity, in particular NK˜antagonistic activity, their preparation, compositions comprising them and their use as a medicine, in particular for the treatment of pain, emesis, anxiety, depression and IBS.