The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2009

Filed:

Mar. 07, 2005
Applicants:

William K. Hagmann, Westfield, NJ (US);

Linus S. Lin, Westfield, NJ (US);

Ping Liu, Westfield, NJ (US);

Richard A. Mumford, Red Bank, NJ (US);

Thomas S. Reger, San Diego, CA (US);

Nicholas D. Smith, San Diego, CA (US);

Nicholas S. Stock, San Diego, CA (US);

Jasmine Zunic, San Diego, CA (US);

Inventors:

William K. Hagmann, Westfield, NJ (US);

Linus S. Lin, Westfield, NJ (US);

Ping Liu, Westfield, NJ (US);

Richard A. Mumford, Red Bank, NJ (US);

Thomas S. Reger, San Diego, CA (US);

Nicholas D. Smith, San Diego, CA (US);

Nicholas S. Stock, San Diego, CA (US);

Jasmine Zunic, San Diego, CA (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/05 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of Formula I are antagonists of VLA-4, and as such are useful in the inhibition or prevention of cell adhesion and cell-adhesion mediated pathologies. These compounds may be formulated into pharmaceutical compositions and are suitable for use in the treatment of inflammatory bowel disease including ulcerative colitis and Crohn's disease, multiple sclerosis, asthma, and rheumatoid arthritis.


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