The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2009
Filed:
Nov. 26, 2002
Applicants:
Antonio Bedalov, Seattle, WA (US);
Daniel E. Gottschling, Seattle, WA (US);
Julian Simon, Seattle, WA (US);
Inventors:
Antonio Bedalov, Seattle, WA (US);
Daniel E. Gottschling, Seattle, WA (US);
Julian Simon, Seattle, WA (US);
Assignee:
Fred Hutchinson Cancer Research Center, Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 31/50 (2006.01);
U.S. Cl.
CPC ...
Abstract
A method for identifying a compound that inhibits the NAD-dependent deacetylase activity of a SIR2 protein is disclosed. These compounds are useful for the treatment of cancers and other diseases, through the activation of silenced genes, through the promotion of apoptosis in cancerous cells, and through the inhibition of transcriptional repressor activity in oncogenes.