The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2009
Filed:
Jan. 26, 2005
Applicants:
E. Antonio Chiocca, Powell, OH (US);
Richard Y. Chung, Boston, MA (US);
Inventors:
E. Antonio Chiocca, Powell, OH (US);
Richard Y. Chung, Boston, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); C12N 15/63 (2006.01); A61K 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to herpes viral mutants and methods of using these viral mutants for selectively targeting tumor cells or other populations of target cells. The viral mutants of the invention are capable of selective targeting due to the use of tumor-specific and/or cell-specific promoters to drive expression of the herpes γ34.5 gene.