The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2009
Filed:
Apr. 18, 2003
Laurie B. Gower, Gainesville, FL (US);
Matthew J. Olszta, Gainesville, FL (US);
Elliot P. Douglas, Gainesville, FL (US);
Sivakumar Munisamy, Gainesville, FL (US);
Donna L. Wheeler, Fort Collins, CO (US);
Laurie B. Gower, Gainesville, FL (US);
Matthew J. Olszta, Gainesville, FL (US);
Elliot P. Douglas, Gainesville, FL (US);
Sivakumar Munisamy, Gainesville, FL (US);
Donna L. Wheeler, Fort Collins, CO (US);
University of Florida Research Foundation, Inc., Gainesville, FL (US);
Abstract
The subject invention concerns a composite comprising an organic fluid-swellable matrix, such as collagen, and mineral phase, such as calcium carbonate or phosphate mineral phase, for use as a biomimetic of bone. In another aspect, the subject invention concerns a process for making a composite involving the inclusion of acidic polymers to a supersaturated mineralizing solution, in order to induce an amorphous liquid-phase precursor to the inorganic mineral, which is then absorbed (pulled by capillary action) into the interstices of the organic matrix, and subsequently mineralizes via solidification and crystallization of the precursor phase. The present invention further concerns a method of treating a patient suffering from a bone defect by applying a biomimetic composite to the bone defect site.