The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2009
Filed:
Jan. 17, 2004
James R. Prudent, Madison, WI (US);
Scott C. Johnson, Sun Prairie, WI (US);
Michael J. Moser, Madison, WI (US);
David J. Marshall, Madison, WI (US);
James R. Prudent, Madison, WI (US);
Scott C. Johnson, Sun Prairie, WI (US);
Michael J. Moser, Madison, WI (US);
David J. Marshall, Madison, WI (US);
EraGen Biosciences, Inc., Madison, WI (US);
Abstract
The present invention provides methods, kits and compositions for high fidelity nucleic acid amplification reactions of target nucleic acids such that specific amplification products that incorporate non-standard bases are produced. The amplification reactions can either be linear or exponential. In some embodiments, the fidelity of the amplification reaction is high enough such that a majority of the amplification products maintain non-standard bases at specific sites designated by the user after a specified number of amplification cycles. In some embodiments, the ratio of non-standard nucleoside triphosphates is greater than the amount of standard nucleoside triphosphates initially present in the reaction mixture.