The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2009
Filed:
Mar. 15, 2006
Lance E. Steward, Irvine, CA (US);
Fernandez-salas Ester, Fullerton, CA (US);
Joseph Francis, Aliso Viejo, CA (US);
Shengwin LI, Irvine, CA (US);
Marcella A. Gilmore, Santa Ana, CA (US);
Kei Roger Aoki, Coto de Caza, CA (US);
Lance E. Steward, Irvine, CA (US);
Fernandez-Salas Ester, Fullerton, CA (US);
Joseph Francis, Aliso Viejo, CA (US);
Shengwin Li, Irvine, CA (US);
Marcella A. Gilmore, Santa Ana, CA (US);
Kei Roger Aoki, Coto de Caza, CA (US);
Allergan, Inc., Irvine, CA (US);
Abstract
The present invention is directed to multivalentneurotoxin derivatives having more than one binding domain directed to a cell surface feature of a target cell. Such modified neurotoxins are useful as therapeutic compositions to prevent exocytosis and secretion by the target cell. Conditions in which such compositions man be useful include, without limitation, disorders of the sensory or motor nervous system, acute or chronic pain, cancer, pancreatitis, hyperhydrosis, glandular disorders, viral infections, cystic fibrosis and the like. The invention is also directed to methods of using and administering such a composition, and methods of treating a given condition using such a composition.