The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2009
Filed:
May. 25, 2007
Mark A. Gallop, Santa Clara, CA (US);
Xuedong Dai, San Jose, CA (US);
Randall A. Scheuerman, Santa Clara, CA (US);
Stephen P. Raillard, Mountain View, CA (US);
Suresh K. Manthati, Cupertino, CA (US);
Fenmei Yao, Mountain View, CA (US);
Thu Phan, Fremont, CA (US);
Maria Ludwikow, Cupertino, CA (US);
GE Peng, Mountain View, CA (US);
Seema Bhat, Santa Clara, CA (US);
Mark A. Gallop, Santa Clara, CA (US);
Xuedong Dai, San Jose, CA (US);
Randall A. Scheuerman, Santa Clara, CA (US);
Stephen P. Raillard, Mountain View, CA (US);
Suresh K. Manthati, Cupertino, CA (US);
Fenmei Yao, Mountain View, CA (US);
Thu Phan, Fremont, CA (US);
Maria Ludwikow, Cupertino, CA (US);
Ge Peng, Mountain View, CA (US);
Seema Bhat, Santa Clara, CA (US);
XenoPort, Inc., Santa Clara, CA (US);
Abstract
Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described.