The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2009

Filed:

Jul. 01, 2002
Applicants:

Evgeny Nudler, New York, NY (US);

Andrei Nedospasov, Moscow, RU;

Inventors:

Evgeny Nudler, New York, NY (US);

Andrei Nedospasov, Moscow, RU;

Assignee:

New York University, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 307/02 (2006.01); A61K 31/18 (2006.01);
U.S. Cl.
CPC ...
Abstract

Biomacromolecules such as proteins are inactivated by hydrophobic ANSA derivatives of the formula: wherein Rand Rare hydrophobic or affinity groups and Ris selected from the group consisting of aminoacyl groups and peptidyl groups upon nitrosation. ANSA derivatives can be designed to selectively kill tumor cells and various pathogens, including bacteria, viruses, and fungi.


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