The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2009
Filed:
Jul. 01, 2005
Applicants:
Charles E. Mckenna, Los Angelese, CA (US);
Boris A. Kashemirov, Los Angeles, CA (US);
Ulrika Tehler, Lund, SE;
John Hilfinger, Ann Arbor, MI (US);
Inventors:
Charles E. McKenna, Los Angelese, CA (US);
Boris A. Kashemirov, Los Angeles, CA (US);
Ulrika Tehler, Lund, SE;
John Hilfinger, Ann Arbor, MI (US);
Assignees:
University of Southern California, Los Angeles, CA (US);
TSRL, Inc., Ann Arbor, MI (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/54 (2006.01); A61K 31/505 (2006.01); A61K 38/05 (2006.01); A61K 38/04 (2006.01); A61K 31/675 (2006.01); C07F 9/02 (2006.01); C07F 9/6512 (2006.01);
U.S. Cl.
CPC ...
Abstract
Cidofovir-based compounds having an amino acid, dipeptide or tripeptide attached to a cidofovir or cyclic cidofovir framework. The compounds show enhanced oral bioavailability and increased binding to the PepT1 transporter. The present invention also provides compositions and methods for treating virus infections, and a method of preparing cidofovir.