The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2009
Filed:
May. 03, 2002
Kai Krohn, Salmentaka, FI;
Vesna Blazevic, Tampere, FI;
Marja Tahtinen, Tampere, FI;
Mart Ustav, Tartu, EE;
Urve Toots, Tartu, EE;
Andres Mannik, Tartu, EE;
Annamari Ranki, Helsinki, FI;
Ene Ustav, Tartu, EE;
Kai Krohn, Salmentaka, FI;
Vesna Blazevic, Tampere, FI;
Marja Tahtinen, Tampere, FI;
Mart Ustav, Tartu, EE;
Urve Toots, Tartu, EE;
Andres Mannik, Tartu, EE;
Annamari Ranki, Helsinki, FI;
Ene Ustav, Tartu, EE;
Fit Biotech Oyj PLC, Tampere, FI;
Abstract
The present invention relates to novel vectors, to DNA vaccines and gene therapeutics containing the vectors, to methods for the preparation of the vectors and DNA vaccines and gene therapeutics containing the vectors, and to therapeutic uses of the vectors. The novel vectors comprise (a) an expression cassette of a gene of a nuclear-anchoring protein, which contains (i) a DNA binding domain capable of binding to a specific DNA sequence and (ii) a functional domain capable of binding to a nuclear component and (b) a multimerized DNA sequence forming a binding site for the anchoring protein, and optionally (c) one or more expression cassettes of a DNA sequence of interest. The vectors lack a papilloma virus origin of replication.