The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2009

Filed:

Nov. 20, 2003
Applicant:

Josef F. Bille, Heidelberg, DE;

Inventor:

Josef F. Bille, Heidelberg, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 3/02 (2006.01); A61B 3/10 (2006.01); A61B 3/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

A system for diagnostically evaluating the health of tissue within the fundus of an eye includes a fs laser source, an adaptive optical assembly, an imaging unit, and a computer. The adaptive optical assembly focuses a laser beam to a focal point in the fundus of the eye, and scans the fundus tissue according to a predetermined scanning pattern. Illumination of anisotropic tissue within the fundus, such as the photoreceptors and the Henle-fiber layer, induces a Second Harmonic Generation (SHG) response. Red photons, with a wavelength (λ) of about 880 nm, are converted to blue photons, with a wavelength of λ/2, through the process of photon conversion. An imaging unit senses the blue photon return light, and uses the return light to generate an image of the fundus. The computer processes the image, and compares it to a template of healthy tissue to evaluate the health of the imaged tissue.


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