The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2009
Filed:
Dec. 21, 2004
Nathan Bryan Mantlo, Brownsburg, IN (US);
Antonio Navarro, Indianapolis, IN (US);
Ashraf Saeed, Westfield, IN (US);
Douglas Linn Gernert, Indianapolis, IN (US);
Tianwei MA, Carmel, IN (US);
Lance Allen Pfeifer, Indianapolis, IN (US);
Nathan Bryan Mantlo, Brownsburg, IN (US);
Antonio Navarro, Indianapolis, IN (US);
Ashraf Saeed, Westfield, IN (US);
Douglas Linn Gernert, Indianapolis, IN (US);
Tianwei Ma, Carmel, IN (US);
Lance Allen Pfeifer, Indianapolis, IN (US);
Eli Lilly and Company, Indianapolis, IN (US);
Abstract
The present invention is directed to compounds represented by the following structural formula, Formula (I): wherein: (a) X is selected from the group consisting of a single bond, O, S, S(O)and N; (b) U is an aliphatic linker; (c) Y is selected from the group consisting of O, C, S, NH and a single bond; (d) W is N, O or S; (e) E is C(R3)(R4)A or A and wherein; (f) A is selected from the group consisting of carboxyl, tetrazole, C-Calkylnitrile, carboxamide, sulfonamide and acylsufonamide. The other substituents are defined in the claims; the compounds are modulators of peroxisome proleferator activated receptors (PPARs) and are useful for the treatment of diabetes and other metabolic disorders.