The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2009
Filed:
Jul. 22, 2005
Jianfeng Chen, Beijing, CN;
Jie Zhong, Beijing, CN;
Zhigang Shen, Beijing, CN;
Jiyao Zhang, Beijing, CN;
Jianfeng Chen, Beijing, CN;
Jie Zhong, Beijing, CN;
Zhigang Shen, Beijing, CN;
Jiyao Zhang, Beijing, CN;
Nanomaterials Technology Pte Ltd., Singapore, SG;
Beijing University of Chemical Technology, Beijing, CN;
Abstract
A novel process for the preparation of amorphous cefuroxime axetil particles and the amorphous cefuroxime axetil particles therefrom are disclosed in the invention. Specifically, the invention is implemented by means of antisolvent recrystallization to prepare the cefuroxime axetil in an amorphous form; particularly, the amorphous ultrafine or even nanosized cefuroxime axetil with a controllable particle size and a narrow particle size distribution. The cefuroxime axetil according to the invention can used to enhance bioavailability, since it is in an amorphous form and has a controllable particle size and a narrow particle size distribution.