The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2009
Filed:
Oct. 11, 2006
James G. Karras, San Marcos, CA (US);
Susan Gregory, San Diego, CA (US);
Susan M. Freier, San Diego, CA (US);
William A. Gaarde, Carlsbad, CA (US);
Mausumee Guha, Carlsbad, CA (US);
James G. Karras, San Marcos, CA (US);
Susan Gregory, San Diego, CA (US);
Susan M. Freier, San Diego, CA (US);
William A. Gaarde, Carlsbad, CA (US);
Mausumee Guha, Carlsbad, CA (US);
ISIS Pharmaceuticals, Inc., Carlsbad, CA (US);
Abstract
Disclosed herein are compounds, compositions and methods for modulating the expression of IL-4R alpha in a cell, tissue or animal. Also provided are methods of target validation. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders related to expression of IL 4R-α, airway hyperresponsiveness, and/or pulmonary inflammation.