The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2009
Filed:
Sep. 24, 2004
Nan Zhang, Bayside, NY (US);
Semiramis Ayral-kaloustian, Tarrytown, NY (US);
Thai Nguyen, Fair Lawn, NJ (US);
Yanzhong Wu, Bronx, NY (US);
Wei Tong, Suffern, NY (US);
Nan Zhang, Bayside, NY (US);
Semiramis Ayral-Kaloustian, Tarrytown, NY (US);
Thai Nguyen, Fair Lawn, NJ (US);
Yanzhong Wu, Bronx, NY (US);
Wei Tong, Suffern, NY (US);
Wyeth, Madison, NJ (US);
Abstract
This invention relates to certain 6-[(substituted)phenyl]triazolopyrimidine compounds or pharmaceutically acceptable salts thereof, and compositions containing said compounds or pharmaceutically acceptable salts thereof, wherein said compounds are anti-cancer agents useful for the treatment of cancer in mammals. This invention further relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal and further provides a method for the treatment or prevention of cancerous tumors that express multiple drug resistance (MDR) or are resistant because of MDR, in a mammal in need thereof which method comprises administering to said mammal an effective amount of said compounds or pharmaceutically acceptable salts thereof. The present invention relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal in need thereof by promotion of microtubule polymerization which comprises administering to said mammal an effective amount of said compounds and pharmaceutically acceptable salts thereof.