The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2009
Filed:
May. 08, 2001
Walter Elger, Berlin, DE;
Alexander Hillisch, Jena, DE;
Annemarie Hedden, Hamburg, DE;
Sigfrid Schwarz, Jena, DE;
Klaus Schollkopf, Berlin, DE;
Walter Elger, Berlin, DE;
Alexander Hillisch, Jena, DE;
Annemarie Hedden, Hamburg, DE;
Sigfrid Schwarz, Jena, DE;
Klaus Schollkopf, Berlin, DE;
Schering AG, Berlin, DE;
Abstract
The invention relates to compounds which, acting as a prodrug and/or support, enable an active agent to be taken up by the erythrocytes and/or an active agent to bind to the erythrocytes. The uptake of these compounds by and/or the binding thereof to the erythrocytes is made possible by a group of formula —SO2NR1R2, wherein R1 and R2, independently of each other, mean a hydrogen atom, an acyl group, an alkyl group, a cycloalkyl group, an aryl group, a cyano group or a hydroxy group. The inventive prodrugs enable active agents such as endogenic substances, natural substances and synthetic substances with therapeutically useful properties which have a high 'first path' effect, to be administered orally effectively or significantly improve the oral activity thereof.