The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2009
Filed:
Dec. 17, 2004
Prabha Ibrahim, Mountain View, CA (US);
Dean Richard Artis, Kensington, CA (US);
Ryan Bremer, Albany, CA (US);
Gaston Habets, Pleasant Hill, CA (US);
Clarence R. Hurt, San Ramon, CA (US);
Shumeye Mamo, Oakland, CA (US);
Marika Nespi, Berkeley, CA (US);
Chao Zhang, Moraga, CA (US);
Jiazhong Zhang, Oakland, CA (US);
Yong Zhu, Union City, CA (US);
Rebecca Zuckerman, Alameda, CA (US);
Heike Krupka, Hayward, CA (US);
Abhinav Kumar, Pleasant Hill, CA (US);
Brian West, San Francisco, CA (US);
Prabha Ibrahim, Mountain View, CA (US);
Dean Richard Artis, Kensington, CA (US);
Ryan Bremer, Albany, CA (US);
Gaston Habets, Pleasant Hill, CA (US);
Clarence R. Hurt, San Ramon, CA (US);
Shumeye Mamo, Oakland, CA (US);
Marika Nespi, Berkeley, CA (US);
Chao Zhang, Moraga, CA (US);
Jiazhong Zhang, Oakland, CA (US);
Yong Zhu, Union City, CA (US);
Rebecca Zuckerman, Alameda, CA (US);
Heike Krupka, Hayward, CA (US);
Abhinav Kumar, Pleasant Hill, CA (US);
Brian West, San Francisco, CA (US);
Plexxikon, Inc., Berkley, CA (US);
Abstract
Compounds active on Ret are described, as well as methods of using such compounds. Also described are crystal structures of Ret surrogates that were determined using X-ray crystallography. The use of such Ret surrogate crystals and structural information can, for example, be used for identifying molecular scaffolds and for developing ligands that bind to and modulate Ret and for identifying improved ligands based on known ligands.