The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2009
Filed:
Jul. 28, 2003
Kazuo Koyama, Kawaguchi, JP;
Shinji Marumoto, Tokyo, JP;
Narihiro Toda, Tokyo, JP;
Keiko Suzuki, Tokyo, JP;
Kazuo Koyama, Kawaguchi, JP;
Shinji Marumoto, Tokyo, JP;
Narihiro Toda, Tokyo, JP;
Keiko Suzuki, Tokyo, JP;
BTG International Limited, London, GB;
Abstract
A compound of the formula (I): wherein Rrepresents C–Calkyl, amino(C–Calkyl)amino, di(C–Calkyl)amino or a nitrogen-containing saturated heterocyclic; Rand Rare the same or different and represent hydrogen or C–Calkyl; Rrepresents C–Calkyl or C–Calkenyl or together with Rrepresents a C–Calkylene; Arom represents aryl or heteroaryl; A represents a C–Calkylene; E represents a single bond, oxygen, sulfur or RNR—, wherein Ris hydrogen or C–Calkenoyl; Xand Xare the same or different and represent oxygen or sulfur; or a pharmacologically acceptable salt or ester thereof. The compound has superior acetylcholinesterase inhibitory action and selective serotonin reuptake inhibitory action, and is useful for treating or preventing Alzheimer's disease, depression, Huntington's chorea, Pick's disease, tardive dyskinesia, compulsive disorders or panic disorders.