The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2009
Filed:
Jan. 21, 2005
Michael J. Frohn, Thousand Oaks, CA (US);
Fang-tsao Hong, Thousand Oaks, CA (US);
Longbin Liu, Thousand Oaks, CA (US);
Patricia Lopez, West Hills, CA (US);
Aaron Siegmund, Ventura, CA (US);
Seifu Tadesse, Simi Valley, CA (US);
Nuria Tamayo, Newbury Park, CA (US);
Michael J. Frohn, Thousand Oaks, CA (US);
Fang-Tsao Hong, Thousand Oaks, CA (US);
Longbin Liu, Thousand Oaks, CA (US);
Patricia Lopez, West Hills, CA (US);
Aaron Siegmund, Ventura, CA (US);
Seifu Tadesse, Simi Valley, CA (US);
Nuria Tamayo, Newbury Park, CA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
The present invention relates to pyrimidinones and pyridones and derivatives thereof, and pharmaceutically acceptable salts thereof. Also included is a method of treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple myeloma, uveititis, acute or chronic myelogenous leukemia, pancreatic β cell destruction, osteoarthritis, rheumatoid spondylitis, gouty arthritis, inflammatory bowel disease, adult respiratory distress syndrome (ARDS), psoriasis, Crohn's disease, allergic rhinitis, ulcerative colitis, anaphylaxis, contact dermatitis, asthma, muscle degeneration, cachexia, Reiter's syndrome, type I diabetes, type II diabetes, bone resorption diseases, graft vs. host reaction, Alzheimer's disease, stroke, myocardial infarction, ischemia reperfusion injury, atherosclerosis, brain trauma, multiple sclerosis, cerebral malaria, sepsis, septic shock, toxic shock syndrome, fever, myalgias due to HIV-1, HIV-2, HIV-3, cytomegalovirus (CMV), influenza, adenovirus, the herpes viruses or herpes zoster infection in a mammal comprising administering an effective amount a compound as described above.