The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2009
Filed:
Oct. 19, 2006
Kazuo Koyama, Kawaguchi, JP;
Shinji Marumoto, Tokyo, JP;
Narihiro Toda, Tokyo, JP;
Hiroshi Kogen, Fuchu, JP;
Keiko Suzuki, Tokyo, JP;
Kazuo Koyama, Kawaguchi, JP;
Shinji Marumoto, Tokyo, JP;
Narihiro Toda, Tokyo, JP;
Hiroshi Kogen, Fuchu, JP;
Keiko Suzuki, Tokyo, JP;
BTG International Limited, London, GB;
Abstract
A compound of the formula (I): wherein Ris a C-Calkyl group, an amino group, a (C-Calkyl)amino group, a di(C-Calkyl)amino group or a nitrogen-containing saturated heterocyclic group; Ris a hydrogen atom or a C-Calkyl group; Arom is an unsubstituted or substituted aryl group or an unsubstituted or substituted heteroaryl group; wherein the substituted aryl group is substituted at 1 to 5 positions and the substituted heteroaryl group is substituted at 1 to 3 positions; and wherein the substituents of the aryl group and of the heteroaryl group are independently selected from the group consisting of halogen atom, C-Calkyl, halogeno C-Calkyl, C-Calkoxy, C-Calkylthio, C-Calkylenedioxy, C-Calkanoyl, C-Calkyloxycarbonyl, amino, C-Calkanoylamino, hydroxyl, mercapto, cyano, nitro and carboxyl; A is a C-Calkylene group; Rtogether with Ris a C-Calkylene group containing a double bond; E is a single bond, an oxygen atom, a sulfur atom or a group of the formula: —NR—, wherein Ris a hydrogen atom or a C-Calkanoyl group; Xand Xare the same or different and are an oxygen atom or a sulfur atom, or a pharmacologically acceptable salt or ester thereof.