The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2009
Filed:
Nov. 15, 2005
Mark Arnold Thomas Blaskovich, Bardon, AU;
Ted Baughman, Bothell, WA (US);
Thomas Little, Redmond, WA (US);
William Patt, Lawrence, KS (US);
Maher Qabar, Sammamish, WA (US);
Lauri Mario Schultz, Batavia, IL (US);
Gangadhar Nagula, Bothell, WA (US);
Jennifer Lynn Gage, Kenmore, WA (US);
James Jeffry Howbert, Bellevue, WA (US);
Mark Arnold Thomas Blaskovich, Bardon, AU;
Ted Baughman, Bothell, WA (US);
Thomas Little, Redmond, WA (US);
William Patt, Lawrence, KS (US);
Maher Qabar, Sammamish, WA (US);
Lauri Mario Schultz, Batavia, IL (US);
Gangadhar Nagula, Bothell, WA (US);
Jennifer Lynn Gage, Kenmore, WA (US);
James Jeffry Howbert, Bellevue, WA (US);
Ceptyr, Inc., Redmond, WA (US);
Abstract
The present invention provides compounds of Formula (I) and Formula (II) that are useful for modulating the biological activity of the protein tyrosine phosphatase-1b (PTP1B) enzyme. Compounds of this invention can be used to treat diseases and/or conditions in which the PTP1B enzyme is a factor. Such diseases and/or conditions include, but are not limited to, Type 1 diabetes, Type 2 diabetes, inadequate glucose tolerance, insulin resistance, obesity, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, low HDL levels, atherosclerosis, vascular restenosis, inflammatory bowel disease, pancreatitis, adipose cell tumors, adipose cell carcinoma, liposarcoma, dyslipidemia, cancer, and neurodegenerative diseases.