The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2009

Filed:

Apr. 28, 2006
Applicants:

Kui-hyun Kim, Daejeon-si, KR;

Jun-hong Min, Yongin-si, KR;

In-ho Lee, Yongin-si, JP;

Ah-gi Kim, Yongin-si, KR;

Inventors:

Kui-hyun Kim, Daejeon-si, KR;

Jun-hong Min, Yongin-si, KR;

In-ho Lee, Yongin-si, JP;

Ah-gi Kim, Yongin-si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/00 (2006.01); G01N 33/53 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided is a method of sensitively detecting nucleic acids in a nucleic acid sample, the method comprising: contacting the sample comprising the nucleic acid with a non-specific nucleic acid binding agent in an electrically conductive fluid medium; contacting the sample comprising the nucleic acid bound to the agent with a nanopore; and applying a voltage to the nanopore and monitoring a current change through the nanopore. The nucleic acid can be sensitively detected because a change in current amplitude through the nanopore is greater than when nucleic aid detection is performed without using an intercalator.


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