The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2009
Filed:
Apr. 26, 2004
Applicants:
Nigel J. Forrow, Oxon, GB;
Gurdial S. Sanghera, Newton, MA (US);
Jared L. Watkin, Oxfordshire, GB;
Stephen Walters, Birmingham, GB;
Inventors:
Nigel J. Forrow, Oxon, GB;
Gurdial S. Sanghera, Newton, MA (US);
Jared L. Watkin, Oxfordshire, GB;
Stephen Walters, Birmingham, GB;
Assignee:
Abbott Laboratories, Alameda, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/327 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention is based on the discovery of NADand NADPmediator compounds that do not bind irreversibly to thiol groups in the active sites of intracellular dehydrogenase enzymes. Such mediator compounds avoid a common mode of enzyme inhibition. The mediators can therefore increase the stability and reliability of the electrical response in amperometric electrodes constructed from NAD- or NADP-dependent enzymes.