The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2009

Filed:

Aug. 06, 2004
Applicants:

Adnan M. M. Mjalli, Oak Ridge, NC (US);

Guoxiang Huang, Greensboro, NC (US);

Murty N. Arimilli, Oak Ridge, NC (US);

Thomas Scott Yokum, Greensboro, NC (US);

Jeff Jiqun Zhu, Greensboro, NC (US);

Muralidhar Bondlela, Greensboro, NC (US);

Inventors:

Adnan M. M. Mjalli, Oak Ridge, NC (US);

Guoxiang Huang, Greensboro, NC (US);

Murty N. Arimilli, Oak Ridge, NC (US);

Thomas Scott Yokum, Greensboro, NC (US);

Jeff Jiqun Zhu, Greensboro, NC (US);

Muralidhar Bondlela, Greensboro, NC (US);

Assignee:

TransTech Pharma, Inc., High Point, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 229/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides aryl and heteroaryl compounds of Formula (I) as described herein, and methods of their preparation. Also provided are pharmaceutical compositions made with the compounds of Formula (I) and methods for making such compositions. The compounds of Formula (I) may activate an erythropoietin receptor and thus, may be useful to induce red blood cell production. The compounds of Formula (I) and compositions including compounds of Formula (I) may be useful in a variety of applications including the management, treatment and/or control of diseases caused at least in part by deficient (or inefficient) EPO production relative to hemoglobin level.


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