The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 10, 2009
Filed:
Aug. 27, 2004
Mark Jozef Albert Waer, Heverlee, BE;
Piet André Maurits Maria Herdewijn, Rotselaar/Wezemaal, BE;
Wolfgang Eugen Pfleiderer, Constance, DE;
Arnaud Didier Marie Marchand, Heverlee, BE;
Steven Cesar Alfons DE Jonghe, Brussels, BE;
Mark Jozef Albert Waer, Heverlee, BE;
Piet André Maurits Maria Herdewijn, Rotselaar/Wezemaal, BE;
Wolfgang Eugen Pfleiderer, Constance, DE;
Arnaud Didier Marie Marchand, Heverlee, BE;
Steven Cesar Alfons De Jonghe, Brussels, BE;
4 AZA Bioscience NV, Leuven, BE;
Abstract
This invention relates to a group of trisubstituted and tetrasubstituted pteridine derivatives, their pharmaceutically acceptable salts, N-oxides, solvates, dihydro- and tetrahydro-derivatives and enantiomers, possessing unexpectedly desirable pharmaceutical properties, in particular which are highly active immunosuppressive agents, and as such are useful in the treatment in transplant rejection and/or in the treatment of certain inflammatory diseases. These compounds are also useful in preventing or treating cardiovascular disorders, allergic conditions, disorders of the central nervous system and cell proliferative disorders.