The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2009

Filed:

Nov. 21, 2003
Applicants:

Masakazu Fujio, Tokyo, JP;

Hiroyuki Satoh, Tokyo, JP;

Shinya Inoue, Tokyo, JP;

Toshifumi Matsumoto, Tokyo, JP;

Yasuhiro Egi, Tokyo, JP;

Taichi Takahashi, Tokyo, JP;

Inventors:

Masakazu Fujio, Tokyo, JP;

Hiroyuki Satoh, Tokyo, JP;

Shinya Inoue, Tokyo, JP;

Toshifumi Matsumoto, Tokyo, JP;

Yasuhiro Egi, Tokyo, JP;

Taichi Takahashi, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/02 (2006.01); A61K 31/47 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to an isoquinoline compound represented by the following formula (I) or (II), an optically active form thereof, a pharmaceutically acceptable salt thereof, a water adduct thereof, a hydrate thereof and a solvate thereof, as well as an agent for the prophylaxis and/or treatment of a disease caused by hyperreactivity of poly(ADP-ribose)polymerase, containing the compound, and a poly(ADP-ribose)polymerase inhibitor containing the compound. In addition, this compound is useful as an agent for the prophylaxis and/or treatment of cerebral infarction, particularly as an agent for the prophylaxis and/or treatment of acute cerebral infarction.


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