The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2009

Filed:

Apr. 04, 2006
Applicants:

Thomas Bannister, Palm Beach Gardens, FL (US);

Cassandra Celatka, Hull, MA (US);

Nizal S. Chandrakumar, North Grafton, MA (US);

Hongfeng Deng, Acton, MA (US);

Zihong Guo, Southbury, CT (US);

Lei Jin, Wellesley, MA (US);

Tsvetelina Lazarova, Brookline, MA (US);

Jian Lin, Walpole, MA (US);

Scott T. Moe, Marlborough, MA (US);

Pamela Nagafuji, Cambridge, MA (US);

Manuel Navia, Lexington, MA (US);

Amy Ripka, Winthrop, MA (US);

Michael J. Rynkiewicz, Boston, MA (US);

Kerry L. Spear, Concord, MA (US);

James E. Stickler, Milton, MA (US);

Roger Xie, Southborough, MA (US);

Inventors:

Thomas Bannister, Palm Beach Gardens, FL (US);

Cassandra Celatka, Hull, MA (US);

Nizal S. Chandrakumar, North Grafton, MA (US);

Hongfeng Deng, Acton, MA (US);

Zihong Guo, Southbury, CT (US);

Lei Jin, Wellesley, MA (US);

Tsvetelina Lazarova, Brookline, MA (US);

Jian Lin, Walpole, MA (US);

Scott T. Moe, Marlborough, MA (US);

Pamela Nagafuji, Cambridge, MA (US);

Manuel Navia, Lexington, MA (US);

Amy Ripka, Winthrop, MA (US);

Michael J. Rynkiewicz, Boston, MA (US);

Kerry L. Spear, Concord, MA (US);

James E. Stickler, Milton, MA (US);

Roger Xie, Southborough, MA (US);

Assignee:

DAIMED, Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 205/08 (2006.01); C07D 205/085 (2006.01); C07D 401/14 (2006.01); C07D 401/12 (2006.01); C07D 401/06 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 403/04 (2006.01); A61K 31/397 (2006.01); A61K 31/506 (2006.01); A61K 31/4427 (2006.01); A61K 31/41 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds are provided which have the structure Wherein A, B, C, D, m, Y, Ra, Rc, Rd, and Rd' are as described herein, and which are useful as inhibitors of tryptase, thrombin, trypsin, Factor Xa, Factor VIIa, Factor XIa, and urokinase-type plasminogen activator and may be employed in preventing and/or treating asthma, chronic asthma, allergic rhinitis, and thrombotic disorders.


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