The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2009

Filed:

Nov. 18, 2005
Applicants:

Darren Whitehouse, Westbrook, CT (US);

Shaojing HU, Hamden, CT (US);

Michael C. Van Zandt, Guilford, CT (US);

Garrett Parker, Branford, CT (US);

Inventors:

Darren Whitehouse, Westbrook, CT (US);

Shaojing Hu, Hamden, CT (US);

Michael C. Van Zandt, Guilford, CT (US);

Garrett Parker, Branford, CT (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/343 (2006.01); C07D 307/91 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are compound and pharmaceutically acceptable salts of formula (I): which are useful in the treatment of metabolic disorders related to insulin resistance, leptin resistance, or hyperglycemia. Compound of the invention include inhibitors of protein tyrosine phosphatase, in particular protein tyrosine phosphatase-1B (PTP-1B), that are useful in the treatment of diabetes and other PTP mediated diseases, such as cancer, neurodegenerative diseases and the like. Also disclosed are pharmaceutical compositions comprising aforementioned conditions using such compounds.


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