The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 03, 2009

Filed:

Jun. 14, 2005
Applicants:

Yuanxi Zhou, Surrey, CA;

Gary J. Bridger, Bellingham, WA (US);

Renato T. Skerlj, Vancouver, CA;

David Bogucki, Surrey, CA;

Wen Yang, Aldergrove, CA;

Elyse Bourque, Langley, CA;

Jonathan Langille, Langley, CA;

Tong-shuang LI, Langley, CA;

Markus Metz, Delta, CA;

Inventors:

Yuanxi Zhou, Surrey, CA;

Gary J. Bridger, Bellingham, WA (US);

Renato T. Skerlj, Vancouver, CA;

David Bogucki, Surrey, CA;

Wen Yang, Aldergrove, CA;

Elyse Bourque, Langley, CA;

Jonathan Langille, Langley, CA;

Tong-Shuang Li, Langley, CA;

Markus Metz, Delta, CA;

Assignee:

Genzyme Corporation, Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4453 (2006.01); C07D 211/58 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to chemokine receptor binding compounds, pharmaceutical compositions and their use. More specifically, the present invention relates to modulators of chemokine receptor activity, preferably modulators of CCR5. These compounds demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).


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