The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2009
Filed:
Mar. 01, 2001
Laurent Francois Andre Hennequin, Reims Cedex, FR;
Graham Charles Crawley, Macclesfield, GB;
Darren Mckerrecher, Macclesfield, GB;
Patrick Ple, Reims Cedex, FR;
Jeffrey Philip Poyser, Macclesfield, GB;
Christine Marie Paul Lambert, Reims Cedex, FR;
Laurent Francois Andre Hennequin, Reims Cedex, FR;
Graham Charles Crawley, Macclesfield, GB;
Darren McKerrecher, Macclesfield, GB;
Patrick Ple, Reims Cedex, FR;
Jeffrey Philip Poyser, Macclesfield, GB;
Christine Marie Paul Lambert, Reims Cedex, FR;
AstraZeneca AB, Sodertalje, CH;
Abstract
The invention concerns the use of a quinazoline derivative of Formula (I) wherein Qincludes a quinazoline ring optionally substituted with a group such as halogeno, trifluoromethyl and cyano, or a group of the formula: Q—X— wherein Xincludes a direct bond and O and Qincludes aryl, aryl-(1-6C)alkyl, heterocyclyl and heterocyclyl-(1-6C)alkyl; each of Rand Ris hydrogen or (1-6C)alkyl; Z includes O, S and NH; and Qincludes aryl and aryl-(1-3C)alkyl or a pharmaceutically-acceptable salt thereof, in the manufacture of a medicament for use in the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human.