The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 2009
Filed:
Apr. 16, 2004
Rena Nishizawa, Mishima-gun, JP;
Yoshikazu Takaoka, Mishima-gun, JP;
Hiromu Habashita, Mishima-gun, JP;
Shiro Shibayama, Tsukuba, JP;
Masaya Kokubo, Mishima-gun, JP;
Rena Nishizawa, Mishima-gun, JP;
Yoshikazu Takaoka, Mishima-gun, JP;
Hiromu Habashita, Mishima-gun, JP;
Shiro Shibayama, Tsukuba, JP;
Masaya Kokubo, Mishima-gun, JP;
Ono Pharmaceuticals Co., Ltd., Osaka, JP;
Abstract
The present invention relates to a spiro-piperidine compound represented by formula (I): wherein Rrepresents hydrogen, an aliphatic hydrocarbon group which may have a substituent(s) or a cyclic group which may have a substituent(s); and ring A represents a 5- to 8-membered cyclic group which may have a substituent(s), a salt thereof, an N-oxide thereof, a quaternary ammonium salt thereof or a solvate thereof, or a prodrug thereof. The compounds represented by formula (I) have chemokine antagonistic action, so that they are useful for prevention and/or treatment of various inflammatory diseases, immune diseases such as autoimmune diseases or allergic diseases, or HIV infection.